AAV Capsid Engineering

AAV Capsid Engineering involves the strategic modification of the viral protein shell to optimise gene delivery. By refining the capsid architecture, it enhances its performance as a gene delivery vehicle—enabling precise cellular targeting, robust immune evasion, and maximized transgene expression. 

ProverBio Gene leverages rational design to select and identify the optimal AAV capsid tailored to your specific project requirements.

• Enhanced Transduction Efficiency: Maximizing viral entry and processing.
• Refined Tissue Tropism: Ensuring high-precision targeting of specific cell types.
• Diminished Immunogenicity: Minimizing host immune detection and neutralizing antibody interference.
• Optimized Dosage Profiles: Achieving therapeutic efficacy with lower viral loads.